Evaluation of Glutathione Levels in Gingival Cervical Fluid in Periodontitis from Stage 1 – Stage 4 among Type 2 Diabetic Patients

Authors

Maha Elsayed, Dentist at General Authority for Health Insurance B.D.S (2013) MUST University, Egypt.Follow
Mai Attia, Professor of Oral Medicine, Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls, Al-Azhar University, Faculty of Oral and Dental Medicine – Misr International University, Cairo, EgyptFollow
Zienab Farid, Lecturer of Oral Medicine , Periodontology, Oral Diagnosis and Radiology Faculty of Dental Medicine for Girls –Al-Azhar University, Cairo, EgyptFollow

Corresponding Author

Elsayed, Maha

Document Type

Original Study

Abstract

Purpose: This study aimed to evaluate if glutathione could be used as a diagnostic biomarker in diabetic patients with stage 1, stage 2, stage 3, and stage 4 periodontitis who were receiving non-surgical periodontal therapy. Material and methods: Twentyeight participants were included, who were separated into four groups, each with seven members. Seven diabetic patients with stage 1 periodontitis were assigned to Group 1, seven diabetic patients with stage 2 periodontitis were assigned to Group 2, and seven diabetic patients with stage 3 periodontitis were assigned to Group 3 and Seven diabetic patients with stage 4 periodontitis were assigned to Group 4. Gingival crevicular fluid (GCF) samples were taken from every individual at baseline (before non-surgical periodontal therapy) and one month after non-surgical periodontal therapy was completed. Results: Glutathione levels in the four groups dramatically improved after non-surgical therapy. Conclusion: Glutathione levels should be considered important indicator for prognosis of the periodontal treatment in patients with periodontal disease.

Keywords

glutathione; Periodontitis; Diabetic patients

How to Cite This Article

Elsayed, Maha; Attia, Mai; and Farid, Zienab (2023) "Evaluation of Glutathione Levels in Gingival Cervical Fluid in Periodontitis from Stage 1 – Stage 4 among Type 2 Diabetic Patients," Al-Azhar Journal of Dentistry: Vol. 10: Iss. 1, Article 28.
DOI: https://doi.org/10.58675/2974-4164.1484

Subject Area

Oral Medicine and Surgical Sciences Issue (Oral Medicine, Oral and Maxillofacial Surgery, Oral Pathology, Oral Biology)