The Effect of Low-Level Laser Therapy as an Adjunct to Non-Surgical Therapy on Inducible Nitric Oxide Synthase Salivary Levels in Different Age Groups of Patients (A Randomized Clinical Trial)

Authors

Alaa Allah Hesham Mousa, Teaching Assistant of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology. Faculty of Dental Medicine for Future University in Egypt.Follow
Hamdy Ahmed Nassar, Professor of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology. Faculty of Dental Medicine for Girls-Al-Azhar University.
Amal Aly Ibrahim Elsaid, Lecturer of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology. Faculty of Dental Medicine for Girls Al-Azhar University.

Document Type

Original Study

Abstract

Purpose: The present clinical investigation aimed to evaluate the effect of low-level laser treatment on the clinical parameters and checking levels of inducible nitric oxide synthase in individuals with stage II periodontitis across various age groups.

Material and methods: The current investigation has been carried out on a total of forty-four (44) locations in forty-four (44) patients. Randomly selected locations were chosen from each studied case, divided into four groups: GroupA consisted of eleven sites in elderly patients who underwent scaling combined with root planning exclusively. GroupB included eleven sites in young patients who also got scaling and root planning exclusively, (Group C) Eleven (11) sites in old age received diode laser therapy and (group D): eleven (11) sites in young age group received low level laser (diode laser). The clinical examination used the following clinical parameters: Clinical attachment level, Plaque index, and Gingival index. An ELISA study was conducted on inducible nitric oxide synthase.

Results: Baseline and 3-month post-operative groups were compared showed significant difference in Inducible Nitric oxide synthase levels which was influenced by the treatment in the young age group (non-surgical and laser), but showed no significant difference in the old age group on both types of treatment (non-surgical and laser).

Conclusion: This clinical investigation shown that whereas non-surgical techniques in conjunction with low-level laser treatment was unsuccessful in the elderly population, it was helpful in the young group with stage II periodontitis.

Keywords

Inducible nitric oxide synthase, Old age, Periodontal disease, Inflammageing, Diode laser

How to Cite This Article

Mousa, Alaa Allah Hesham; Nassar, Hamdy Ahmed; and Elsaid, Amal Aly Ibrahim (2024) "The Effect of Low-Level Laser Therapy as an Adjunct to Non-Surgical Therapy on Inducible Nitric Oxide Synthase Salivary Levels in Different Age Groups of Patients (A Randomized Clinical Trial)," Al-Azhar Journal of Dentistry: Vol. 12: Iss. 1, Article 1.
DOI: https://doi.org/10.58675/2974-4164.1650

Subject Area

Oral Medicine and Surgical Sciences Issue (Oral Medicine, Oral and Maxillofacial Surgery, Oral Pathology, Oral Biology)