Effects of Vitamin D on Growth Inhibition of Head and Neck Squamous Cell Carcinoma. (In vitro study)
Document Type
Original Study
Abstract
Objective: To assess the anti-cancer capacity of vitamin D in head and neck squamous cell carcinoma cell line. Materials and Methods: vitamin D cytotoxic effect and cell apoptosis effect were evaluated using Prestoblue cell viability assay and Flow Cytometry. Results: Vitamin D was found to inhibit the cell growth in a dose-dependent manner in head and neck squamous cell carcinoma JHU-29 cell line at three days’ treatment. However, it was not found to cause significant apoptosis at one day treatment. Conclusion: vitamin D inhibits the growth of head and neck squamous cell carcinoma in a dose-dependent manner.
Keywords
Head and Neck Squamous Cell; carcinoma; Vitamin D; apoptosis
How to Cite This Article
Hussein, Heba
(2017)
"Effects of Vitamin D on Growth Inhibition of Head and Neck Squamous Cell Carcinoma. (In vitro study),"
Al-Azhar Journal of Dentistry: Vol. 4:
Iss.
4, Article 6.
DOI: https://doi.org/10.21608/adjg.2017.5285