The Synergetic Effect of Silver Diamine Fluoride with Potassium Iodide and Grape Seed Extract on Dentin Remineralization

Authors

Fatma Hussein, Lecturer of Operative Dentistry, Faculty of Dental Medicine for Girls, AL-Azhar University Cairo, Egypt.Follow
Sara N. Hashem, Lecturer of Pedodontics and Oral Health, Faculty of Dental Medicine for Girls, AL-Azhar University, Cairo, Egypt.Follow
Safaa Elsayed, Lecturer of Pedodontics and Oral Health, Faculty of Dental Medicine for Girls, AL-Azhar University, Cairo, Egypt.Follow

Corresponding Author

Hussein, Fatma

Document Type

Original Study

Abstract

Purpose: This study was conducted to evaluate the synergetic effect of using silver diamine fluoride containing potassium iodide and grape seed extract on dentin microhardness. Materials and Methods: Sixty freshly extracted human deciduous second molars were enrolled in this study. Sixty dentin discs were cut from the crown and were randomly divided into four groups according to the applied treatment after dentin demineralization, (15 samples each). In the first group, samples were received no treatment, only stored in artificial saliva (positive control), in the second group, samples were treated with silver diamine fluoride containing potassium iodide only, in the second group, samples were treated with grape seed extract only (GSE), in the third group, samples were treated with silver diamine fluoride containing potassium iodide (SDF), whereas in the fourth group, samples were treated with combined therapy of grape seed extract followed with silver diamine fluoride containing potassium iodide (GSE+SDF). Microhardness measurements were taken for each dentin disc at baseline, after demineralization, and after treatment. Results: There was a statistically significant increase in dentin microhardness after each treatment as compared to the demineralized dentin microhardness. The mean percent change of dentin microhardness was statistically significant increased in GSE, SDF, and GSE+SDF groups when compared to the control group. Conclusions: Considering the limitations of this study, monotherapy of GSE, SDF solution, and their combination can be recommended to enhance the micro-hardness of demineralized dentin. SDF applications after GSE improved the micro-hardness of demineralized dentin when compared to the monotherapy of each treatment.

Keywords

Grape seed extract; Silver Diamine Fluoride; Synergistic effect; Microhardness

How to Cite This Article

Hussein, Fatma; Hashem, Sara N.; and Elsayed, Safaa (2021) "The Synergetic Effect of Silver Diamine Fluoride with Potassium Iodide and Grape Seed Extract on Dentin Remineralization," Al-Azhar Journal of Dentistry: Vol. 8: Iss. 1, Article 9.
DOI: https://doi.org/10.21608/adjg.2021.43369.1296

Subject Area

Restorative Dentistry Issue (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)