Pulp Tissue Response to Platelets Rich Plasma, Platelets Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Materials

Authors

Sarah D. Shaheen, Assistant lecturer of operative dentistry, Faculty of dental medicine, Misr University for Science and Technology MUST, Cairo, EgyptFollow
Maha A. Niazy, Professor of operative dentistry, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, Egypt.Follow
Wael E. Jamil, Professor and head of operative dentistry, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, EgyptFollow
Ashraf M. Abu-Seida, Professor of Surgery, Anesthesiology & Radiology, Faculty of veterinary Medicine, Cairo University, Egypt

Corresponding Author

Shaheen, Sarah D.

Document Type

Original Study

Abstract

Purpose: to evaluate the biological response of the dog teeth to Platelets Rich plasma (PRP), Platelets Rich fibrin (PRF) and mineral trioxide aggregate (MTA) as pulp capping materials. Material and Methods: A total of 90 teeth of dogs were included. Class V cavities were prepared. Pulp exposure was performed in the middle of cavity floor. The teeth were divided into three groups of 30 teeth according to the material used; A1: PRP, A2: PRF and A3: MTA. Glass ionomer restoration was applied as restoration for the cavities. The tissue response to the materials was assessed at three different post-operative periods of 7, 30, 60 days. The animal was sacrificed. Histomorphometric analysis was performed. Result: the results showed high inflammatory cells count at 7 days for all treated groups; PRP treated teeth showed the highest at 7 days, while PRF showed the least. At 1 and 2 months postoperatively no significant difference was found between all the treated groups. For dentin bridge scores; there was no significant difference between all the materials at 7 days and 1 month. At 2 months; the MTA treated teeth recorded the greatest dentin bridge score as compared to all treated teeth. As for integrity of odontoblast score; results showed no significant difference between different materials at 7 days and 1 month. The MTA treated teeth showed the highest score as compared to PRP and PRF at 2 months. Conclusion: Among the three different materials, PRP and PRF appeared to be promising pulp capping agents.

Keywords

Keywords: Platelets rich plasma; Platelets rich fibrin; Mineral trioxide aggregate

How to Cite This Article

Shaheen, Sarah D.; Niazy, Maha A.; Jamil, Wael E.; and Abu-Seida, Ashraf M. (2021) "Pulp Tissue Response to Platelets Rich Plasma, Platelets Rich Fibrin and Mineral Trioxide Aggregate as Pulp Capping Materials," Al-Azhar Journal of Dentistry: Vol. 8: Iss. 4, Article 4.
DOI: https://doi.org/10.21608/adjg.2021.37107.1280

Subject Area

Restorative Dentistry Issue (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)