Evaluation of Photodynamic Therapy Using Diode Laser with Photosensitizer in Treatment of Chronic Periodontitis

Authors

Doaa Bhgaat, Demonstrator of Oral Medicine, Periodontology, Radiology and Oral Diagnosis Department, Faculty of Dental Medicine, Al -Azhar university, Cairo, Egypt.Follow
Hamdy Nassar, Professor of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Department, Faculty of dental medicine for Girls, Al-Azhar University, Cairo, Egypt.
Naglaa Elkilani, Professor and the Head of Oral Medicine, Periodontology, Oral Diagnosis and Dental Radiology Department, Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Eman Kandeel, Professor and the head of Applied and Organic Chemistry Department, Faculty of Science for Girls, Al-Azhar University, Cairo, Egypt.

Corresponding Author

Bhgaat, Doaa

Document Type

Original Study

Abstract

Purpose: The current clinical study was conducted to evaluate clinical and biochemical effects of photodynamic therapy in treatment of periodontal disease. Material and methods: The current study was conducted on twenty-eight (28) sites in fourteen (14) patients. A spilt-mouth design was used, sites were randomly selected from each patient, and assigned into two groups:(control group A) fourteen (14) sites received scaling and root planning only, and (test group B): fourteen (14) sites received PDT (Curcumin as photosensitizer agent was irradiated by diode laser beam) and another group without any laser beam in oral cavity, 5 patients received SRP only. Clinical parameters included probing pocket depth (PPD), clinical attachment level (CAL), Plaque index (PI), and gingival index (GI) were used to make clinical evaluation. ELISA analysis of human P.gingivalis IGg was done. Results: Comparison between the groups at baseline, one week and one month was showed significant difference in human P.gingivalis IGg which decreased in test group more than in control group. Conclusion: This clinical study illustrated that SRP in combination with PDT can be effective especially when used as an adjunctive therapy to the mechanical conditioning of the periodontal pockets. Although using Curcumin as natural photosensitizer agent have great effect on enhancement of inflammation in patients with periodontal disease.

Keywords

Periodontitis; photodynamic therapy; Nano-Curcumin; Laser

How to Cite This Article

Bhgaat, Doaa; Nassar, Hamdy; Elkilani, Naglaa; and Kandeel, Eman (2022) "Evaluation of Photodynamic Therapy Using Diode Laser with Photosensitizer in Treatment of Chronic Periodontitis," Al-Azhar Journal of Dentistry: Vol. 9: Iss. 3, Article 13.
DOI: https://doi.org/10.21608/adjg.2022.58090.1330

Subject Area

Oral Medicine and Surgical Sciences Issue (Oral Medicine, Oral and Maxillofacial Surgery, Oral Pathology, Oral Biology)