Preparation, Characterization and Evaluation of a Poly Methyl Methacrylate Bone Cement Modified by Montmorillonite Loaded with Silver Nano Particles

Authors

Horia Elsherif, Assistant Researcher at Restorative and Dental Biomaterials Department, Oral and Dental Research Institute, National Research Centre, Cairo, Egypt.Follow
Sayed Saniour, Professor of Dental Materials, Faculty of Dentistry, Cairo University, Cairo, Egypt.Follow
Inas Motawea, Professor of Dental Biomaterials, Dean of Faculty of Dental Medicine for Girls, Al-Azhar University, Cairo, Egypt.Follow
Hisham Essawy, Professor of Polymer Science, Department of Polymers and Pigments, Institute of Chemical Industries Research, National Research Centre, Cairo, Egypt.Follow
Mostafa Abd El-Gany, Professor of Removable Prosthodontics, Faculty of Dental Medicine for Girls, Al-Azhar University.Follow
Dalia Zaki, Professor at Restorative and Dental Materials Department, Oral and Dental Research Institute, National Research Centre, Cairo, Egypt.Follow

Corresponding Author

Elsherif, Horia

Document Type

Original Study

Abstract

Purpose: The aim of this study was to prepare and characterize poly methyl methacrylate (PMMA) composite bone cement filled with montmorillonite (MMT) and loaded with silver nanoparticles (AgNPs). Materials and methods: AgNPs were synthesized by the chemical reducing method. Characterization was done using Field emission scanning electron microscope (FE-SEM), X-ray diffraction analysis (XRD) and Thermogravimetric analysis (TGA). Two and four weight percentages of MMT powder and the prepared MMT/AgNPs powder were added to the bone cement.A total of 75 PMMA bone cement specimens were prepared and divided into 5 groups (control group, PMMT/MMT 2%, PMMT/MMT 4%, PMMT/MMTAgNps 2% and PMMT/MMTAgNps 4%). Then they were tested regarding the compressive strength, flexural strength and antibacterial activity. Results: SEM images showed the layered MMT with light spots indicating presence of AgNPs that was confirmed by XRD; while TGA showed its thermal stability. Compressive strength results revealed statistically insignificant difference between the control and the tested groups while the 4% PMMA/MMT showed statistically significant higher values than the 2%. Statisticallyinsignificant difference in flexural strength results were found between the 2% and 4% concentrations within the PMMA/MMT/AgNPs group, and within the PMMA/MMT group. Antibacterial results revealed statistical significant differences in all the tested groups (p < 0.001). Conclusion: MMT could be used as a controlled delivery system to hold AgNPs that proved to have antibacterial effect when added to PMMA cement. Addition of 4% MMT to PMMA bone cement improved its compressive strength.

Keywords

polymethyl methacrylate; silver nanoparticles; montmorillonite

How to Cite This Article

Elsherif, Horia; Saniour, Sayed; Motawea, Inas; Essawy, Hisham; Abd El-Gany, Mostafa; and Zaki, Dalia (2022) "Preparation, Characterization and Evaluation of a Poly Methyl Methacrylate Bone Cement Modified by Montmorillonite Loaded with Silver Nano Particles," Al-Azhar Journal of Dentistry: Vol. 9: Iss. 3, Article 8.
DOI: https://doi.org/10.21608/adjg.2022.76299.1391

Subject Area

Restorative Dentistry Issue (Removable Prosthodontics, Fixed Prosthodontics, Endodontics, Dental Biomaterials, Operative Dentistry)